Drug Standards
TARGETMOL CHEMICALS INC Ganoderic acid H 1MG
Also available in 5 mg and bulk. Please contact Fisher for quotes. Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kB, resulting in the suppression of secretion of uPA. Purity 95%
Selleck Chemical LLC Levosimendan 50mg 141505-33-1
Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Edetate calcium disodium
Edetate (EDTA) calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning
Sigma Aldrich Fine Chemicals Biosciences Raspberry ketone United States Pharmacopeia (USP) Reference Standard | 5471-51-2 | MFCD00002394 | 100MG
Raspberry ketone United States Pharmacopeia (USP) Reference Standard | Mol Wt: 164.2 | 5471-51-2 | MFCD00002394 | 100MG
Apexbio Technology LLC Camostat Mesilate 59721-29-8 100mg
Camostat Mesilate (59721-29-8) is a small-molecule inhibitor targeting trypsin-like serine proteases It is designed to suppress protease activity thereby modulating processes such as epithelial sodium channel (ENaC) function and airway surface liquid homeostasis Camostat Mesilate exerts its biological activity primarily through protease inhibition In cell-based studies using airway epithelial cells Camostat Mesilate demonstrates ENaC activity suppression with an IC50 value of 50 nM Based on these pharmacological properties Camostat Mesilate holds research potential in studies of respiratory physiology and pathophysiology particularly those investigating ENaC-mediated ion transport in airway epithelial cell models
Sigma Aldrich Fine Chemicals Biosciences Proline European Pharmacopoeia (EP) Reference Standard | 147-85-3 | MFCD00064318 |
Proline European Pharmacopoeia (EP) Reference Standard | Mol Wt: 115.13 | 147-85-3 | MFCD00064318 |
TARGETMOL CHEMICALS INC Y-29794 Tosylate 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes.Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor. Purity 99.1%
Sigma Aldrich Fine Chemicals Biosciences Pimozide | 2062-78-4 | MFCD00055081 | 500mg
Pimozide | Purity: 98% | MW: 461.55 | 2062-78-4 | MFCD00055081 | 500mg
Medchemexpress LLC Budesonide impurity C | 1040085-99-1 | MFCD29920082 | 98.6% | 430.53 g/mol | C25H34O6 | 10 MG
Budesonide impurity C is a chemical impurity of the corticosteroid budesonide, supplied as a research reference material for analytical characterization, impurity profiling, and analytical method development in laboratory and quality-control workflows.
- Used for impurity profiling and analytical method development.
- Purity 98.6%.
- Molecular formula C25H34O6.
- Molecular weight 430.53 g/mol.
- CAS number 1040085-99-1 for unambiguous identification.
- Available in small research pack sizes (10 mg).
Medchemexpress LLC Flavopiridol hydrochloride | 131740-09-5 | MFCD26792554 | 438.30 g/mol | C21H21Cl2NO5 | 500 MG
Flavopiridol hydrochloride (alvocidib hydrochloride) is a broad-spectrum ATP-competitive inhibitor of cyclin-dependent kinases used in biochemical and cell-based research to study cell cycle and transcription. Reported IC50 values include CDK1 = 30 nM, CDK2 = 170 nM, and CDK4 = 100 nM. The compound is soluble in DMSO and water and has documented storage recommendations.
- Broad-spectrum CDK inhibitor with low-nanomolar potency.
- Useful for cell cycle and transcription studies in vitro.
- Soluble in DMSO and water at research concentrations.
- Documented solubility in common solvents and mixed vehicles for formulation.
- Stable when stored sealed; solution stability noted at -80°C (1 year) and -20°C (6 months).
Medchemexpress LLC Flavopiridol hydrochloride (alvocidib hydrochloride) | 131740-09-5 | MFCD26792554 | 99.7% | 438.30 | C21H21Cl2NO5 | 1 ML
Flavopiridol hydrochloride (alvocidib hydrochloride) is an ATP-competitive inhibitor of cyclin-dependent kinases used in research to probe cell cycle regulation, autophagy, and HIV-related pathways. It inhibits CDK1, CDK2, and CDK4 with reported IC50 values of approximately 30 nM, 170 nM, and 100 nM, respectively. Supplied as a solid for solution preparation, it has a molecular weight of 438.30 and high purity for laboratory experiments.
- ATP-competitive inhibitor of cyclin-dependent kinases
- Inhibits CDK1, CDK2, and CDK4 with reported IC50s of ~30, 170, 100 nM
- High purity suitable for research applications
- Supplied as solid for preparation of working solutions
- Useful for studies of cell cycle, autophagy, and HIV-related pathways
Apexbio Technology LLC Naphazoline HCl 550-99-2 10mM (in 1mL DMSO)
Naphazoline HCl (CAS 550-99-2) is a synthetic imidazoline derivative that acts as a sympathomimetic amine It primarily targets -adrenergic receptors on vascular smooth muscle inducing vasoconstriction through the activation of these receptors This property leads to reduced blood flow and decreased vascular congestion particularly in ocular tissues Naphazoline HCl is frequently employed in research to investigate adrenergic signaling pathways and to model vasoconstrictive mechanisms in vitro and in vivo Its pharmacological profile makes it a valuable tool for studies involving vascular responses and ocular pharmacodynamics
Selleck Chemical LLC Regorafenib (BAY 73-4506) 10mM/1mL 755037-03-7 Fluoro-Sorafenib, Resihance, Stivarga
Regorafenib (BAY 73-4506, Fluoro-Sorafenib, Resihance, Stivarga) is a multi-target inhibitor for¿VEGFR1,¿VEGFR2,¿VEGFR3,¿PDGFR?,¿Kit (c-Kit),¿RET (c-RET)¿and¿Raf-1¿with¿IC50¿of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces¿autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.